IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks

Focal adhesion kinase (FAK) mediates tumor cell–intrinsic behaviors that promote tumor growth and metastasis. We previously showed that FAK also induces the expression of inflammatory genes that inhibit antitumor immunity in the microenvironment. Here, we identified a crucial, previously unknown rol...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Serrels, Bryan, McGivern, Niamh, Canel, Marta, Byron, Adam, Johnson, Sarah C, Mcsorley, Henry, Quinn, Niall, Taggart, David, Von Kreigsheim, Alex, Anderton, Stephen M, Serrels, Alan, Frame, Margaret C
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128400/
https://ncbi.nlm.nih.gov/pubmed/29208683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan8355
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