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IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks
Focal adhesion kinase (FAK) mediates tumor cell–intrinsic behaviors that promote tumor growth and metastasis. We previously showed that FAK also induces the expression of inflammatory genes that inhibit antitumor immunity in the microenvironment. Here, we identified a crucial, previously unknown rol...
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| Pubblicato in: | Sci Signal |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6128400/ https://ncbi.nlm.nih.gov/pubmed/29208683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan8355 |
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