Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3(+) Regulatory T Cells via a miR-342-Dependent Mechanism

Glucocorticoids (GC) are the mainstay treatment option for inflammatory conditions. Despite the broad usage of GC, the mechanisms by which GC exerts its effects remain elusive. Here, utilizing murine autoimmune and allergic inflammation models, we report that Foxp3(+) regulatory T (Treg) cells are i...

詳細記述

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書誌詳細
出版年:Immunity
主要な著者: Kim, Dongkyun, Nguyen, Quang Tam, Lee, Juyeun, Lee, Sung Hwan, Janocha, Allison, Kim, Sohee, Le, Hongnga T., Dvorina, Nina, Weiss, Kelly, Cameron, Mark J., Asosingh, Kewal, Erzurum, Serpil C., Baldwin, William M., Lee, Ju-Seog, Min, Booki
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793548/
https://ncbi.nlm.nih.gov/pubmed/32707034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.07.002
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