Steroid responsiveness in Foxp3(+) regulatory T cells determines steroid sensitivity during allergic airway inflammation in mice

Glucocorticoids are a highly effective first-line treatment option for many inflammatory diseases including asthma. Some patients develop a steroid-resistant condition; yet, the cellular and molecular mechanisms underlying steroid resistance remain largely unknown. Here, we utilized a murine model o...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Nguyen, Quang Tam, Kim, Dongkyun, Iamsawat, Supinya, Le, Hongnga T., Kim, Sohee, Qiu, Kevin T., Hinds, Terry D., Bazeley, Peter, O’Shea, John J., Choi, Jaehyuk, Asosingh, Kewal, Erzurum, Serpil C., Min, Booki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323959/
https://ncbi.nlm.nih.gov/pubmed/34301840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2100251
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