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Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3(+) Regulatory T Cells via a miR-342-Dependent Mechanism

Glucocorticoids (GC) are the mainstay treatment option for inflammatory conditions. Despite the broad usage of GC, the mechanisms by which GC exerts its effects remain elusive. Here, utilizing murine autoimmune and allergic inflammation models, we report that Foxp3(+) regulatory T (Treg) cells are i...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Kim, Dongkyun, Nguyen, Quang Tam, Lee, Juyeun, Lee, Sung Hwan, Janocha, Allison, Kim, Sohee, Le, Hongnga T., Dvorina, Nina, Weiss, Kelly, Cameron, Mark J., Asosingh, Kewal, Erzurum, Serpil C., Baldwin, William M., Lee, Ju-Seog, Min, Booki
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793548/
https://ncbi.nlm.nih.gov/pubmed/32707034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.07.002
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