Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3(+) Regulatory T Cells via a miR-342-Dependent Mechanism

Glucocorticoids (GC) are the mainstay treatment option for inflammatory conditions. Despite the broad usage of GC, the mechanisms by which GC exerts its effects remain elusive. Here, utilizing murine autoimmune and allergic inflammation models, we report that Foxp3(+) regulatory T (Treg) cells are i...

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Gepubliceerd in:Immunity
Hoofdauteurs: Kim, Dongkyun, Nguyen, Quang Tam, Lee, Juyeun, Lee, Sung Hwan, Janocha, Allison, Kim, Sohee, Le, Hongnga T., Dvorina, Nina, Weiss, Kelly, Cameron, Mark J., Asosingh, Kewal, Erzurum, Serpil C., Baldwin, William M., Lee, Ju-Seog, Min, Booki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793548/
https://ncbi.nlm.nih.gov/pubmed/32707034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.07.002
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