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IL-27 attenuates autoimmune neuroinflammation via Treg/Lag3-dependent but IL-10-independent mechanisms in vivo
Interleukin(IL)-27 regulates immune responses in inflammation. The underlying mechanism of IL-27 functions has long been attributed to its ability to induce IL-10 production in activated CD4 T cells. Here, we report that Foxp3(+) regulatory T cells (Tregs) are the main target cells of IL-27 mediatin...
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| 出版年: | J Immunol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6401226/ https://ncbi.nlm.nih.gov/pubmed/30700587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800898 |
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