An IL-27/Lag3 axis enhances Foxp3(+) regulatory T cell suppressive function and therapeutic efficacy

Foxp3-expressing regulatory T cells (Tregs) are central regulators of immune homeostasis and tolerance. As it has been suggested that proper Treg function is compromised under inflammatory conditions, seeking for a pathway that enhances or stabilizes Treg function is a subject of considerable intere...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Do, Jeong-su, Visperas, Anabelle, Sanogo, Yibayiri Osee, Bechtel, Jennifer J., Dvorina, Nina, Kim, Sohee, Jang, Eunjung, Stohlman, Stephen A., Shen, Bo, Fairchild, Robert L., Baldwin, William M., Vignali, Dario A. A., Min, Booki
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662649/
https://ncbi.nlm.nih.gov/pubmed/26013006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.45
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