Steroid responsiveness in Foxp3(+) regulatory T cells determines steroid sensitivity during allergic airway inflammation in mice

Glucocorticoids are a highly effective first-line treatment option for many inflammatory diseases including asthma. Some patients develop a steroid-resistant condition; yet, the cellular and molecular mechanisms underlying steroid resistance remain largely unknown. Here, we utilized a murine model o...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Nguyen, Quang Tam, Kim, Dongkyun, Iamsawat, Supinya, Le, Hongnga T., Kim, Sohee, Qiu, Kevin T., Hinds, Terry D., Bazeley, Peter, O’Shea, John J., Choi, Jaehyuk, Asosingh, Kewal, Erzurum, Serpil C., Min, Booki
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323959/
https://ncbi.nlm.nih.gov/pubmed/34301840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2100251
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