Steroid responsiveness in Foxp3(+) regulatory T cells determines steroid sensitivity during allergic airway inflammation in mice

Glucocorticoids are a highly effective first-line treatment option for many inflammatory diseases including asthma. Some patients develop a steroid-resistant condition; yet, the cellular and molecular mechanisms underlying steroid resistance remain largely unknown. Here, we utilized a murine model o...

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Vydáno v:J Immunol
Hlavní autoři: Nguyen, Quang Tam, Kim, Dongkyun, Iamsawat, Supinya, Le, Hongnga T., Kim, Sohee, Qiu, Kevin T., Hinds, Terry D., Bazeley, Peter, O’Shea, John J., Choi, Jaehyuk, Asosingh, Kewal, Erzurum, Serpil C., Min, Booki
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323959/
https://ncbi.nlm.nih.gov/pubmed/34301840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2100251
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