Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice

Vascular dysregulation and cholinergic basal forebrain degeneration are both early pathological events in the development of Alzheimer’s disease (AD). Acetylcholine contributes to localised arterial dilatation and increased cerebral blood flow (CBF) during neurovascular coupling via activation of en...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol Commun
Egile Nagusiak: Nizari, Shereen, Wells, Jack A., Carare, Roxana O., Romero, Ignacio A., Hawkes, Cheryl A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791879/
https://ncbi.nlm.nih.gov/pubmed/33413694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01108-z
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