Failure of Perivascular Drainage of β‐amyloid in Cerebral Amyloid Angiopathy

In Alzheimer's disease, amyloid‐β (Aβ) accumulates as insoluble plaques in the brain and deposits in blood vessel walls as cerebral amyloid angiopathy (CAA). The severity of CAA correlates with the degree of cognitive decline in dementia. The distribution of Aβ in the walls of capillaries and a...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Hawkes, Cheryl A., Jayakody, Nimeshi, Johnston, David A., Bechmann, Ingo, Carare, Roxana O.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
MINI‐SYMPOSIUM: Pericytes, the Neurovascular Unit and Neurodegeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029317/
https://ncbi.nlm.nih.gov/pubmed/24946077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12159
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