Editorial: Clearance Pathways for Amyloid-β. Significance for Alzheimer's Disease and Its Therapy

Por Carare, Roxana O.
Publicado no Front Aging Neurosci (2017)

Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet

Por Nizari, Shereen, Carare, Roxana O., Hawkes, Cheryl A.
Publicado no Sci Rep (2016)

Amyloid and tau in the brain in sporadic Alzheimer’s disease: defining the chicken and the egg

Por Hawkes, Cheryl A., Carare, Roxana O., Weller, Roy O.
Publicado em 2014

Cerebral amyloid angiopathy in the aetiology and immunotherapy of Alzheimer disease

Por Weller, Roy O, Preston, Stephen D, Subash, Malavika, Carare, Roxana O
Publicado em 2009

Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interaction

Por Teeling, Jessica L., Carare, Roxana O., Glennie, Martin J., Perry, V. Hugh
Publicado em 2012

The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy

Por Morris, Alan W. J., Carare, Roxana O., Schreiber, Stefanie, Hawkes, Cheryl A.
Publicado em 2014

Vascular, glial, and lymphatic immune gateways of the central nervous system

Por Engelhardt, Britta, Carare, Roxana O., Bechmann, Ingo, Flügel, Alexander, Laman, Jon D., Weller, Roy O.
Publicado no Acta Neuropathol (2016)

Arterial Pulsations cannot Drive Intramural Periarterial Drainage: Significance for Aβ Drainage

Por Diem, Alexandra K., MacGregor Sharp, Matthew, Gatherer, Maureen, Bressloff, Neil W., Carare, Roxana O., Richardson, Giles
Publicado no Front Neurosci (2017)

Disruption of Arterial Perivascular Drainage of Amyloid-β from the Brains of Mice Expressing the Human APOE ε4 Allele

Por Hawkes, Cheryl A., Sullivan, Patrick M., Hands, Sarah, Weller, Roy O., Nicoll, James A. R., Carare, Roxana O.
Publicado em 2012

Hemisphere Asymmetry of Response to Pharmacologic Treatment in an Alzheimer’s Disease Mouse Model

Por Manousopoulou, Antigoni, Saito, Satoshi, Yamamoto, Yumi, Al-Daghri, Nasser M., Ihara, Masafumi, Carare, Roxana O., Garbis, Spiros D.
Publicado no J Alzheimers Dis (2016)

A Simulation Model of Periarterial Clearance of Amyloid-β from the Brain

Por Diem, Alexandra K., Tan, Mingyi, Bressloff, Neil W., Hawkes, Cheryl, Morris, Alan W. J., Weller, Roy O., Carare, Roxana O.
Publicado no Front Aging Neurosci (2016)

Intravital imaging in spontaneously hypertensive stroke-prone rats-a pilot study

Por Niklass, Solveig, Stoyanov, Stoyan, Garz, Cornelia, Bueche, Celine Z, Mencl, Stine, Reymann, Klaus, Heinze, Hans-Jochen, Carare, Roxana O, Kleinschnitz, Christoph, Schreiber, Stefanie
Publicado em 2014

Hypertension drives parenchymal β-amyloid accumulation in the brain parenchyma

Por Bueche, Celine Z, Hawkes, Cheryl, Garz, Cornelia, Vielhaber, Stefan, Attems, Johannes, Knight, Robert T, Reymann, Klaus, Heinze, Hans-Jochen, Carare, Roxana O, Schreiber, Stefanie
Publicado em 2014

Vascular basement membranes as pathways for the passage of fluid into and out of the brain

Por Morris, Alan W. J., Sharp, Matthew MacGregor, Albargothy, Nazira J., Fernandes, Rute, Hawkes, Cheryl A., Verma, Ajay, Weller, Roy O., Carare, Roxana O.
Publicado no Acta Neuropathol (2016)

Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases

Por Bakker, Erik N. T. P., Bacskai, Brian J., Arbel-Ornath, Michal, Aldea, Roxana, Bedussi, Beatrice, Morris, Alan W. J., Weller, Roy O., Carare, Roxana O.
Publicado no Cell Mol Neurobiol (2016)

Hypercholesterolemia induced cerebral small vessel disease

Por Kraft, Peter, Schuhmann, Michael K., Garz, Cornelia, Jandke, Solveig, Urlaub, Daniela, Mencl, Stine, Zernecke, Alma, Heinze, Hans-Jochen, Carare, Roxana O., Kleinschnitz, Christoph, Schreiber, Stefanie
Publicado no PLoS One (2017)

Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy()

Por Keable, Abby, Fenna, Kate, Yuen, Ho Ming, Johnston, David A., Smyth, Neil R., Smith, Colin, Salman, Rustam Al-Shahi, Samarasekera, Neshika, Nicoll, James A.R., Attems, Johannes, Kalaria, Rajesh N., Weller, Roy O., Carare, Roxana O.
Publicado no Biochim Biophys Acta (2016)

Clearance systems in the brain—implications for Alzheimer disease

Por Tarasoff-Conway, Jenna M., Carare, Roxana O., Osorio, Ricardo S., Glodzik, Lidia, Butler, Tracy, Fieremans, Els, Axel, Leon, Rusinek, Henry, Nicholson, Charles, Zlokovic, Berislav V., Frangione, Blas, Blennow, Kaj, Ménard, Joël, Zetterberg, Henrik, Wisniewski, Thomas, de Leon, Mony J.
Publicado no Nat Rev Neurol (2015)

Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways

Por Wojtas, Aleksandra M., Kang, Silvia S., Olley, Benjamin M., Gatherer, Maureen, Shinohara, Mitsuru, Lozano, Patricia A., Liu, Chia-Chen, Kurti, Aishe, Baker, Kelsey E., Dickson, Dennis W., Yue, Mei, Petrucelli, Leonard, Bu, Guojun, Carare, Roxana O., Fryer, John D.
Publicado no Proc Natl Acad Sci U S A (2017)

Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid

Por Maki, Takakuni, Okamoto, Yoko, Carare, Roxana O, Hase, Yoshiki, Hattori, Yorito, Hawkes, Cheryl A, Saito, Satoshi, Yamamoto, Yumi, Terasaki, Yasukazu, Ishibashi-Ueda, Hatsue, Taguchi, Akihiko, Takahashi, Ryosuke, Miyakawa, Taihei, Kalaria, Raj N, Lo, Eng H, Arai, Ken, Ihara, Masafumi
Publicado em 2014