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A Simulation Model of Periarterial Clearance of Amyloid-β from the Brain

The accumulation of soluble and insoluble amyloid-β (Aβ) in the brain indicates failure of elimination of Aβ from the brain with age and Alzheimer's disease (AD). There is a variety of mechanisms for elimination of Aβ from the brain. They include the action of microglia and enzymes together wit...

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Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Diem, Alexandra K., Tan, Mingyi, Bressloff, Neil W., Hawkes, Cheryl, Morris, Alan W. J., Weller, Roy O., Carare, Roxana O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751273/
https://ncbi.nlm.nih.gov/pubmed/26903861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00018
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