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Selective targeting of perivascular macrophages for clearance of β-amyloid in cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA), the deposition of β-amyloid (Aβ) peptides in leptomeningeal and cortical blood vessels, affects the majority of patients with Alzheimer's disease (AD). Evidence suggests that vascular amyloid deposits may result from impaired clearance of neuronal Aβ along per...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hawkes, Cheryl A., McLaurin, JoAnne
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633563/
https://ncbi.nlm.nih.gov/pubmed/19164591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805453106
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