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Selective targeting of perivascular macrophages for clearance of β-amyloid in cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA), the deposition of β-amyloid (Aβ) peptides in leptomeningeal and cortical blood vessels, affects the majority of patients with Alzheimer's disease (AD). Evidence suggests that vascular amyloid deposits may result from impaired clearance of neuronal Aβ along per...

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Detalles Bibliográficos
Main Authors: Hawkes, Cheryl A., McLaurin, JoAnne
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633563/
https://ncbi.nlm.nih.gov/pubmed/19164591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805453106
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