Failure of Perivascular Drainage of β‐amyloid in Cerebral Amyloid Angiopathy

In Alzheimer's disease, amyloid‐β (Aβ) accumulates as insoluble plaques in the brain and deposits in blood vessel walls as cerebral amyloid angiopathy (CAA). The severity of CAA correlates with the degree of cognitive decline in dementia. The distribution of Aβ in the walls of capillaries and a...

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Bibliographische Detailangaben
Veröffentlicht in:Brain Pathol
Hauptverfasser: Hawkes, Cheryl A., Jayakody, Nimeshi, Johnston, David A., Bechmann, Ingo, Carare, Roxana O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2014
Schlagworte:
MINI‐SYMPOSIUM: Pericytes, the Neurovascular Unit and Neurodegeneration
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029317/
https://ncbi.nlm.nih.gov/pubmed/24946077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12159
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