Failure of Perivascular Drainage of β‐amyloid in Cerebral Amyloid Angiopathy

In Alzheimer's disease, amyloid‐β (Aβ) accumulates as insoluble plaques in the brain and deposits in blood vessel walls as cerebral amyloid angiopathy (CAA). The severity of CAA correlates with the degree of cognitive decline in dementia. The distribution of Aβ in the walls of capillaries and a...

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Publicado en:Brain Pathol
Autores principales: Hawkes, Cheryl A., Jayakody, Nimeshi, Johnston, David A., Bechmann, Ingo, Carare, Roxana O.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2014
Materias:
MINI‐SYMPOSIUM: Pericytes, the Neurovascular Unit and Neurodegeneration
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029317/
https://ncbi.nlm.nih.gov/pubmed/24946077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12159
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