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Recombinant orthopoxvirus primes colon cancer for checkpoint inhibitor and cross-primes T cells for anti-tumor and anti-viral immunity
While it is known that oncolytic viruses can inflame and recruit immune cells to otherwise immunosuppressed tumor microenvironments, the influence of the anti-viral immune response on anti-tumor immunity is less clear across viral platforms and tumor types. CF33 is a recombinant orthopoxvirus backbo...
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| Publicat a: | Mol Cancer Ther |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7790874/ https://ncbi.nlm.nih.gov/pubmed/33262221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0405 |
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