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A Novel Chimeric Poxvirus Encoding hNIS Is Tumor-Tropic, Imageable, and Synergistic with Radioiodine to Sustain Colon Cancer Regression

Colon cancer has a high rate of recurrence even with good response to modern therapies. Novel curative adjuncts are needed. Oncolytic viral therapy has shown preclinical promise against colon cancer but lacks robust efficacy in clinical trials and raises regulatory concerns without real-time trackin...

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Библиографические подробности
Опубликовано в: :Mol Ther Oncolytics
Главные авторы: Warner, Susanne G., Kim, Sang-In, Chaurasiya, Shyambabu, O’Leary, Michael P., Lu, Jianming, Sivanandam, Venkatesh, Woo, Yanghee, Chen, Nanhai G., Fong, Yuman
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495072/
https://ncbi.nlm.nih.gov/pubmed/31061881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.04.001
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