A Novel Chimeric Poxvirus Encoding hNIS Is Tumor-Tropic, Imageable, and Synergistic with Radioiodine to Sustain Colon Cancer Regression

Colon cancer has a high rate of recurrence even with good response to modern therapies. Novel curative adjuncts are needed. Oncolytic viral therapy has shown preclinical promise against colon cancer but lacks robust efficacy in clinical trials and raises regulatory concerns without real-time trackin...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Warner, Susanne G., Kim, Sang-In, Chaurasiya, Shyambabu, O’Leary, Michael P., Lu, Jianming, Sivanandam, Venkatesh, Woo, Yanghee, Chen, Nanhai G., Fong, Yuman
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495072/
https://ncbi.nlm.nih.gov/pubmed/31061881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.04.001
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