Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer characterized by complex metabolic adaptations that promote survival in a severely hypoxic and nutrient limited tumor microenvironment (TME). Modeling microenvironmental influences in cell culture has been challenging, and technical limitatio...

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Vydáno v:Cell Metab
Hlavní autoři: Biancur, Douglas E., Kapner, Kevin, Yamamoto, Keisuke, Banh, Robert S., Neggers, Jasper E., Sohn, Albert S.W., Wu, Warren, Manguso, Robert T., Brown, Adam, Root, David E., Aguirre, Andrew J., Kimmelman, Alec C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790858/
https://ncbi.nlm.nih.gov/pubmed/33152323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.10.018
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