Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer characterized by complex metabolic adaptations that promote survival in a severely hypoxic and nutrient limited tumor microenvironment (TME). Modeling microenvironmental influences in cell culture has been challenging, and technical limitatio...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Biancur, Douglas E., Kapner, Kevin, Yamamoto, Keisuke, Banh, Robert S., Neggers, Jasper E., Sohn, Albert S.W., Wu, Warren, Manguso, Robert T., Brown, Adam, Root, David E., Aguirre, Andrew J., Kimmelman, Alec C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790858/
https://ncbi.nlm.nih.gov/pubmed/33152323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.10.018
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