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Selective autophagy of MHC-I promotes immune evasion of pancreatic cancer

Major histocompatibility complex class I (MHC-I) is a key molecule in anti-tumor adaptive immunity. MHC-I is essential for endogenous antigen presentation by cancer cells and subsequent recognition and clearance by CD8(+) T cells. Defects in MHC-I expression occur frequently in several cancers, lead...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Yamamoto, Keisuke, Venida, Anthony, Perera, Rushika M., Kimmelman, Alec C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469632/
https://ncbi.nlm.nih.gov/pubmed/32459143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1769973
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