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Selective autophagy of MHC-I promotes immune evasion of pancreatic cancer

Major histocompatibility complex class I (MHC-I) is a key molecule in anti-tumor adaptive immunity. MHC-I is essential for endogenous antigen presentation by cancer cells and subsequent recognition and clearance by CD8(+) T cells. Defects in MHC-I expression occur frequently in several cancers, lead...

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Yamamoto, Keisuke, Venida, Anthony, Perera, Rushika M., Kimmelman, Alec C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469632/
https://ncbi.nlm.nih.gov/pubmed/32459143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1769973
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