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The plasticity of pancreatic cancer metabolism in tumor progression and therapeutic resistance

Pancreatic ductal adenocarcinoma (PDA) is an aggressive cancer that is highly refractory to the current standards of care. The difficulty in treating this disease is due to a number of different factors, including altered metabolism. In PDA, the metabolic rewiring favors anabolic reactions which sup...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Rev Cancer
Main Authors: Biancur, Douglas E., Kimmelman, Alec C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345383/
https://ncbi.nlm.nih.gov/pubmed/29702208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2018.04.011
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