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The plasticity of pancreatic cancer metabolism in tumor progression and therapeutic resistance

Pancreatic ductal adenocarcinoma (PDA) is an aggressive cancer that is highly refractory to the current standards of care. The difficulty in treating this disease is due to a number of different factors, including altered metabolism. In PDA, the metabolic rewiring favors anabolic reactions which sup...

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Библиографические подробности
Опубликовано в: :Biochim Biophys Acta Rev Cancer
Главные авторы: Biancur, Douglas E., Kimmelman, Alec C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345383/
https://ncbi.nlm.nih.gov/pubmed/29702208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2018.04.011
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