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Harnessing metabolic dependencies in pancreatic cancers.
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with a 5-year survival rate of <10%. The tumour microenvironment (TME) of PDAC is characterized by excessive fibrosis and deposition of extracellular matrix, termed desmoplasia. This unique TME leads to high interstitial press...
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| Publicado no: | Nat Rev Gastroenterol Hepatol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8249349/ https://ncbi.nlm.nih.gov/pubmed/33742165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41575-021-00431-7 |
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