Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) tumors have a nutrient poor, desmoplastic, and highly innervated tumor microenvironment. Although, neurons can release stimulatory factors to accelerate PDAC tumorigenesis, the metabolic contribution of peripheral axons has not been explored. We found that per...

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Vydáno v:Cell
Hlavní autoři: Banh, Robert S., Biancur, Douglas E., Yamamoto, Keisuke, Sohn, Albert S.W., Walters, Beth, Kuljanin, Miljan, Gikandi, Ajami, Wang, Huamin, Mancias, Joseph D., Schneider, Robert J., Pacold, Michael E., Kimmelman, Alec C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100789/
https://ncbi.nlm.nih.gov/pubmed/33142117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.10.016
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