Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) tumors have a nutrient poor, desmoplastic, and highly innervated tumor microenvironment. Although, neurons can release stimulatory factors to accelerate PDAC tumorigenesis, the metabolic contribution of peripheral axons has not been explored. We found that per...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Banh, Robert S., Biancur, Douglas E., Yamamoto, Keisuke, Sohn, Albert S.W., Walters, Beth, Kuljanin, Miljan, Gikandi, Ajami, Wang, Huamin, Mancias, Joseph D., Schneider, Robert J., Pacold, Michael E., Kimmelman, Alec C.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100789/
https://ncbi.nlm.nih.gov/pubmed/33142117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.10.016
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