Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brain

Type 2 diabetes mellitus (T2D), characterised by peripheral insulin resistance, is a risk factor for dementia. In addition to its contribution to small and large vessel disease, T2D may directly damage cells of the brain neurovascular unit. In this study, we investigated the transcriptomic changes i...

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Detaylı Bibliyografya
Yayımlandı:Acta Neuropathol Commun
Asıl Yazarlar: Bury, Joanna J., Chambers, Annabelle, Heath, Paul R., Ince, Paul G., Shaw, Pamela J., Matthews, Fiona E., Brayne, Carol, Simpson, Julie E., Wharton, Stephen B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788898/
https://ncbi.nlm.nih.gov/pubmed/33407907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01109-y
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