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Neuronal DNA damage response‐associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer‐type pathology

AIMS: Oxidative damage and an associated DNA damage response (DDR) are evident in mild cognitive impairment and early Alzheimer's disease, suggesting that neuronal dysfunction resulting from oxidative DNA damage may account for some of the cognitive impairment not fully explained by Alzheimer‐t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuropathol Appl Neurobiol
मुख्य लेखकों: Simpson, Julie E., Ince, Paul G., Minett, Thais, Matthews, Fiona E., Heath, Paul R., Shaw, Pamela J., Goodall, Emily, Garwood, Claire J., Ratcliffe, Laura E., Brayne, Carol, Rattray, Magnus, Wharton, Stephen B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102584/
https://ncbi.nlm.nih.gov/pubmed/26095650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12252
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