Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brain

Type 2 diabetes mellitus (T2D), characterised by peripheral insulin resistance, is a risk factor for dementia. In addition to its contribution to small and large vessel disease, T2D may directly damage cells of the brain neurovascular unit. In this study, we investigated the transcriptomic changes i...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Acta Neuropathol Commun
Main Authors: Bury, Joanna J., Chambers, Annabelle, Heath, Paul R., Ince, Paul G., Shaw, Pamela J., Matthews, Fiona E., Brayne, Carol, Simpson, Julie E., Wharton, Stephen B.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788898/
https://ncbi.nlm.nih.gov/pubmed/33407907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01109-y
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki