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Human and mouse PD-L1: similar molecular structure, but different druggability profiles
In the development of PD-L1-blocking therapeutics, it is essential to transfer initial in vitro findings into proper in vivo animal models. Classical immunocompetent mice are attractive due to high accessibility and low experimental costs. However, it is unknown whether inter-species differences in...
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| Veröffentlicht in: | iScience |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7788105/ https://ncbi.nlm.nih.gov/pubmed/33437940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101960 |
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