Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint

[Image: see text] Immune checkpoint blockade is one of the most promising strategies of cancer immunotherapy. However, unlike classical targeted therapies, it is currently solely based on expensive monoclonal antibodies, which often inflict immune-related adverse events. Herein, we propose a novel s...

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Vydáno v:J Med Chem
Hlavní autoři: Konieczny, Magdalena, Musielak, Bogdan, Kocik, Justyna, Skalniak, Lukasz, Sala, Dominik, Czub, Miroslawa, Magiera-Mularz, Katarzyna, Rodriguez, Ismael, Myrcha, Maja, Stec, Malgorzata, Siedlar, Maciej, Holak, Tad A., Plewka, Jacek
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2020
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584369/
https://ncbi.nlm.nih.gov/pubmed/32936638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01260
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