Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint

[Image: see text] Immune checkpoint blockade is one of the most promising strategies of cancer immunotherapy. However, unlike classical targeted therapies, it is currently solely based on expensive monoclonal antibodies, which often inflict immune-related adverse events. Herein, we propose a novel s...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Konieczny, Magdalena, Musielak, Bogdan, Kocik, Justyna, Skalniak, Lukasz, Sala, Dominik, Czub, Miroslawa, Magiera-Mularz, Katarzyna, Rodriguez, Ismael, Myrcha, Maja, Stec, Malgorzata, Siedlar, Maciej, Holak, Tad A., Plewka, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584369/
https://ncbi.nlm.nih.gov/pubmed/32936638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01260
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