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CA-170 – A Potent Small-Molecule PD-L1 Inhibitor or Not?
CA-170 is currently the only small-molecule modulator in clinical trials targeting PD-L1 and VISTA proteins – important negative checkpoint regulators of immune activation. The reported therapeutic results to some extent mimic those of FDA-approved monoclonal antibodies overcoming the limitations of...
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| Pubblicato in: | Molecules |
|---|---|
| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6695792/ https://ncbi.nlm.nih.gov/pubmed/31374878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24152804 |
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