CA-170 – A Potent Small-Molecule PD-L1 Inhibitor or Not?

CA-170 is currently the only small-molecule modulator in clinical trials targeting PD-L1 and VISTA proteins – important negative checkpoint regulators of immune activation. The reported therapeutic results to some extent mimic those of FDA-approved monoclonal antibodies overcoming the limitations of...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Molecules
Egile Nagusiak: Musielak, Bogdan, Kocik, Justyna, Skalniak, Lukasz, Magiera-Mularz, Katarzyna, Sala, Dominik, Czub, Miroslawa, Stec, Malgorzata, Siedlar, Maciej, Holak, Tad A., Plewka, Jacek
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695792/
https://ncbi.nlm.nih.gov/pubmed/31374878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24152804
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