Preoperative Carfilzomib and Lulizumab based desensitization prolongs graft survival in a sensitized NHP model.

Sensitized patients are difficult to transplant due to pre-formed anti-donor immunity. We have previously reported successful desensitization using carfilzomib and belatacept in a non-human primate (NHP) model. Here we evaluated selective blockade of the co-stimulatory signal (CD28-B7) with Lulizuma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Kidney Int
Prif Awduron: Schroder, Paul M., Schmitz, Robin, Fitch, Zachary W., Ezekian, Brian, Yoon, Janghoon, Choi, Ashley Y., Manook, Miriam, Barbas, Andrew, Leopardi, Frank, Song, Mingqing, Farris, Alton B., Collins, Bradley, Kwun, Jean, Knechtle, Stuart J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785689/
https://ncbi.nlm.nih.gov/pubmed/32898569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2020.08.020
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