Pretransplant Desensitization with Costimulation Blockade and Proteasome Inhibitor Reduces DSA and Delays Antibody-Mediated Rejection in Highly Sensitized Nonhuman Primate Kidney Transplant Recipients

BACKGROUND: Patients with broad HLA sensitization have poor access to donor organs, high mortality while waiting for kidney transplant, and inferior graft survival. Although desensitization strategies permit transplantation via lowering of donor-specific antibodies, the B cell–response axis from ger...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Ezekian, Brian, Schroder, Paul M., Mulvihill, Michael S., Barbas, Andrew, Collins, Bradley, Freischlag, Kyle, Yoon, Janghoon, Yi, John S., Smith, Felicitas, Olaso, Danae, Saccoccio, Frances M., Permar, Sallie, Farris, Alton B., Kwun, Jean, Knechtle, Stuart J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900797/
https://ncbi.nlm.nih.gov/pubmed/31658991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019030304
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados