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Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates
The detrimental effects of donor-directed antibodies in sensitized transplant patients remain a difficult immunologic barrier to successful organ transplantation. Antibody removal is often followed by rebound. Proteasome inhibitors (PIs) deplete antibody-producing plasma cells (PCs) but have shown m...
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| Publicat a: | Blood Adv |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737135/ https://ncbi.nlm.nih.gov/pubmed/29296858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017010991 |
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