Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients

Previous evidence suggests that a homeostatic germinal center (GC) response may limit bortezomib desensitization therapy. We evaluated the combination of costimulation blockade with bortezomib in a sensitized non-human primate kidney transplant model. Sensitized animals were treated with bortezomib,...

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Publicat a:Am J Transplant
Autors principals: Burghuber, Christopher K., Manook, Miriam, Ezekian, Brian, Gibby, Adriana C., Leopardi, Frank V., Song, Minqing, Jenks, Jennifer, Saccoccio, Frances, Permar, Sallie, Farris, Alton B., Iwakoshi, Neal N., Kwun, Jean, Knechtle, Stuart J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185755/
https://ncbi.nlm.nih.gov/pubmed/30102844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15067
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