Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients

Previous evidence suggests that a homeostatic germinal center (GC) response may limit bortezomib desensitization therapy. We evaluated the combination of costimulation blockade with bortezomib in a sensitized non-human primate kidney transplant model. Sensitized animals were treated with bortezomib,...

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Publicado en:Am J Transplant
Autores principales: Burghuber, Christopher K., Manook, Miriam, Ezekian, Brian, Gibby, Adriana C., Leopardi, Frank V., Song, Minqing, Jenks, Jennifer, Saccoccio, Frances, Permar, Sallie, Farris, Alton B., Iwakoshi, Neal N., Kwun, Jean, Knechtle, Stuart J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185755/
https://ncbi.nlm.nih.gov/pubmed/30102844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15067
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