Costimulation blockade alters germinal center responses and prevents antibody-mediated rejection

De novo donor-specific antibody (DSA) after organ transplantation promotes antibody-mediated rejection (AMR) and causes late graft loss. Previously, we demonstrated that depletion using anti-CD3 immunotoxin (IT) combined with tacrolimus and alefacept (AMR regimen) reliably induced early DSA producti...

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Bibliografiset tiedot
Päätekijät: Kim, Eugenia J, Kwun, Jean, Gibby, Adriana C, Hong, Jung Joo, Farris, Alton B, Iwakoshi, Neal N, Villinger, Francois, Kirk, Allan D, Knechtle, Stuart J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985346/
https://ncbi.nlm.nih.gov/pubmed/24354871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12526
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