Preoperative Carfilzomib and Lulizumab based desensitization prolongs graft survival in a sensitized NHP model.

Sensitized patients are difficult to transplant due to pre-formed anti-donor immunity. We have previously reported successful desensitization using carfilzomib and belatacept in a non-human primate (NHP) model. Here we evaluated selective blockade of the co-stimulatory signal (CD28-B7) with Lulizuma...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Schroder, Paul M., Schmitz, Robin, Fitch, Zachary W., Ezekian, Brian, Yoon, Janghoon, Choi, Ashley Y., Manook, Miriam, Barbas, Andrew, Leopardi, Frank, Song, Mingqing, Farris, Alton B., Collins, Bradley, Kwun, Jean, Knechtle, Stuart J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785689/
https://ncbi.nlm.nih.gov/pubmed/32898569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2020.08.020
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