ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1

Inflammation and cell death are closely linked arms of the host immune response to infection, which when carefully balanced ensure host survival. One example of this balance is the tightly regulated transition from TNFR1-associated pro-inflammatory complex I to pro-death complex II. By contrast, her...

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Publicat a:Nat Commun
Autors principals: Muendlein, Hayley I., Connolly, Wilson M., Magri, Zoie, Smirnova, Irina, Ilyukha, Vladimir, Gautam, Avishekh, Degterev, Alexei, Poltorak, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782486/
https://ncbi.nlm.nih.gov/pubmed/33397971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20357-z
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