Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation

Receptor-interacting protein kinase 1 (RIPK1) and 3 (RIPK3) are well known for their capacity to drive necroptosis via mixed-lineage kinase-like domain (MLKL). Recently, RIPK1/3 kinase activity has been shown to drive inflammation via activation of MAPK signaling. However, the regulatory mechanisms...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Muendlein, Hayley I., Sarhan, Joseph, Liu, Beiyun C., Connolly, Wilson M., Schworer, Stephen A., Smirnova, Irina, Tang, Amy Y., Ilyukha, Vladimir, Pietruska, Jodie, Tahmasebi, Soroush, Sonenberg, Nahum, Degterev, Alexei, Poltorak, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183097/
https://ncbi.nlm.nih.gov/pubmed/31968247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.12.073
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