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ZEB1 and oncogenic Ras constitute a regulatory switch for stimulus‐dependent E‐cadherin downregulation

E‐cadherin, an epithelial cell–specific cell adhesion molecule, has both promoting and suppressing effects on tumor invasion and metastasis. It is often downregulated during cancer progression through gene deletion/mutation, transcriptional repression, or epigenetic silencing. We describe a novel re...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Otake, Shigeo, Itoh, Yuka, Omata, Chiho, Saitoh, Masao, Miyazawa, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780036/
https://ncbi.nlm.nih.gov/pubmed/33068045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14701
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