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ZEB1 and oncogenic Ras constitute a regulatory switch for stimulus‐dependent E‐cadherin downregulation

E‐cadherin, an epithelial cell–specific cell adhesion molecule, has both promoting and suppressing effects on tumor invasion and metastasis. It is often downregulated during cancer progression through gene deletion/mutation, transcriptional repression, or epigenetic silencing. We describe a novel re...

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書目詳細資料
發表在:Cancer Sci
Main Authors: Otake, Shigeo, Itoh, Yuka, Omata, Chiho, Saitoh, Masao, Miyazawa, Keiji
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780036/
https://ncbi.nlm.nih.gov/pubmed/33068045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14701
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