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δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells

Abnormal DNA methylation at the C-5 position of cytosine (5mC) of CpG dinucleotides is a well-known epigenetic feature of cancer. Levels of E-cadherin, which is regularly expressed in epithelial tissues, are frequently reduced in epithelial tumors due to transcriptional repression, sometimes accompa...

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Publicado en:Cancer Med
Autores principales: Fukagawa, Akihiko, Ishii, Hiroki, Miyazawa, Keiji, Saitoh, Masao
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312126/
https://ncbi.nlm.nih.gov/pubmed/25315069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.347
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