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δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells

Abnormal DNA methylation at the C-5 position of cytosine (5mC) of CpG dinucleotides is a well-known epigenetic feature of cancer. Levels of E-cadherin, which is regularly expressed in epithelial tissues, are frequently reduced in epithelial tumors due to transcriptional repression, sometimes accompa...

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Bibliografske podrobnosti
izdano v:Cancer Med
Main Authors: Fukagawa, Akihiko, Ishii, Hiroki, Miyazawa, Keiji, Saitoh, Masao
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312126/
https://ncbi.nlm.nih.gov/pubmed/25315069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.347
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