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δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells
Abnormal DNA methylation at the C-5 position of cytosine (5mC) of CpG dinucleotides is a well-known epigenetic feature of cancer. Levels of E-cadherin, which is regularly expressed in epithelial tissues, are frequently reduced in epithelial tumors due to transcriptional repression, sometimes accompa...
Gespeichert in:
| Veröffentlicht in: | Cancer Med |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312126/ https://ncbi.nlm.nih.gov/pubmed/25315069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.347 |
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