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Lipid membranes influence the ability of small molecules to inhibit huntingtin fibrillization

Several diseases, including Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease (HD), are associated with specific proteins aggregating and depositing within tissues and/or cellular compartments. The aggregation of these proteins is characterized by the formation of extended, β-sheet...

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Detalles Bibliográficos
Publicado en:Biochemistry
Main Authors: Beasley, Maryssa, Stonebraker, Alyssa R., Hasan, Iraj, Kapp, Kathryn L., Liang, Barry J., Agarwal, Garima, Groover, Sharon, Sedeghi, Faezeh, Legleiter, Justin
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778521/
https://ncbi.nlm.nih.gov/pubmed/31608620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00739
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