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Lipid headgroups alter huntingtin aggregation on membranes

Huntington’s Disease is a fatal neurodegenerative disorder caused by expansion of a glutamine repeat region (polyQ) beyond a critical threshold within exon1 of the huntingtin protein (htt). As a consequence of polyQ expansion, htt associates into a variety of aggregate species that are thought to un...

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Detaylı Bibliyografya
Yayımlandı:Biochim Biophys Acta Biomembr
Asıl Yazarlar: Beasley, Maryssa, Groover, Sharon, Valentine, Stephen, Legleiter, Justin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7742038/
https://ncbi.nlm.nih.gov/pubmed/33130095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2020.183497
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