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Lipid headgroups alter huntingtin aggregation on membranes
Huntington’s Disease is a fatal neurodegenerative disorder caused by expansion of a glutamine repeat region (polyQ) beyond a critical threshold within exon1 of the huntingtin protein (htt). As a consequence of polyQ expansion, htt associates into a variety of aggregate species that are thought to un...
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| Publicado en: | Biochim Biophys Acta Biomembr |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7742038/ https://ncbi.nlm.nih.gov/pubmed/33130095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2020.183497 |
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