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Investigating the interactions of the first 17 amino acid residues of Huntingtin with lipid vesicles using mass spectrometry and molecular dynamics

The first 17 amino acid residues of Huntingtin protein (Nt17 of htt) are thought to play an important role in the protein’s function; Nt17 is one of two membrane binding domains in htt. In this study the binding ability of Nt17 peptide with vesicles comprised of two subclasses of phospholipids is st...

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Vydáno v:J Mass Spectrom
Hlavní autoři: Karanji, Ahmad Kiani, Beasely, Maryssa, Sharif, Daud, Ranjbaran, Ali, Legleiter, Justin, Valentine, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7342490/
https://ncbi.nlm.nih.gov/pubmed/31756784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.4470
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