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Investigating the interactions of the first 17 amino acid residues of Huntingtin with lipid vesicles using mass spectrometry and molecular dynamics

The first 17 amino acid residues of Huntingtin protein (Nt17 of htt) are thought to play an important role in the protein’s function; Nt17 is one of two membrane binding domains in htt. In this study the binding ability of Nt17 peptide with vesicles comprised of two subclasses of phospholipids is st...

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Détails bibliographiques
Publié dans:J Mass Spectrom
Auteurs principaux: Karanji, Ahmad Kiani, Beasely, Maryssa, Sharif, Daud, Ranjbaran, Ali, Legleiter, Justin, Valentine, Stephen J.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7342490/
https://ncbi.nlm.nih.gov/pubmed/31756784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.4470
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